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miR-17−92 transgenic mice develop hyperplasia of peripheral lymphoid tissues and have reduced life span. (a) The survival rate of 25 TG/TG and 16 control mice. (b) Haematoxylin and eosin (H&E), CD3 and B220, and MOMA-1 staining of the spleens of 20-week old TG/TG and control mice. CD3 (red) and B220 (blue), and MOMA-1 (red) staining was performed on cryo-sections, and H&E staining was performed on paraffin sections. The black bar indicates 1 mm in length.
