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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Nat Immunol. 2008 Mar 9;9(4):405–414. doi: 10.1038/ni1575

Figure 5.

Figure 5

Enhanced proliferation and survival of miR-17−92 transgenic lymphocytes. (a) Enhanced proliferation of miR-17−92 transgenic lymphocytes. MACS-purified CD4+CD62L+ T cells and B2 cells from TG/TG and control mice were labeled with CFSE and treated with indicated stimuli. CFSE dilution was determined by flow cytometry at indicated time points. (b) Overlay of TG/TG CD4+ T cells stimulated with anti-CD3 and control CD4+ T cells stimulated with anti-CD3 and CD28 from the experiment shown in (a). (c) Cell cycle analysis of CD4+ T cells on day 2 after in vitro activation as described in (a).