TABLE 3.

AdoMet, AdoHcy, and the AdoMet/AdoHcy ratio in the liver of Shmt1 null mice on an ad libitum chow diet

The Shmt1 null mice were on a mixed background of C57Bl/6, BALB/c, and 129SvEv. Data represent means ± S.E. Differences between genotypes were analyzed by Student's t test. p values ≤0.05 were considered significantly different.

Strain	Shmt1 genotype	n	AdoMet	AdoHcy	AdoMet/AdoHcy
			pmol/μg protein	pmol/μg protein
C57Bl/6	Shmt1+/+	9	0.33 ± 0.07	0.51 ± 0.12	0.66 ± 0.08
129SvEv	Shmt1+/+	8	0.32 ± 0.07	2.64 ± 0.51	0.13 ± 0.03
BALB/c	Shmt1+/+	9	0.71 ± 0.16	2.70 ± 0.39	0.32 ± 0.07
All strains	Shmt1+/+	26	0.46 ± 0.07	1.92 ± 0.29	0.38 ± 0.06
129SvEv. C57Bl/6.BALB/c	Shmt1-/-	11	1.02 ± 0.32	0.72 ± 0.24	1.50 ± 0.12
p value, all strains Shmt1+/+vs. Shmt1-/-			0.02	0.02	<0.0001