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. Author manuscript; available in PMC: 2008 Sep 12.
Published in final edited form as: J Nat Prod. 2006 Mar;69(3):351–355. doi: 10.1021/np050327j

Figure 3.

Figure 3

Comparison of effect of turmeric fraction (TF) vs. purified curcuminoids (CURC) on incidence of arthritis vs. hepatic granuloma formation. Female Lewis rats were injected on day 0 with SCW (25 μg/g) or vehicle. Botanical extracts or vehicle alone ip injections were begun 4 days prior to SCW administration and continued on a daily basis until 10 days after SCW injection at which time treatment frequency decreased to 5 days/week. Incidence of joint swelling at day 28 was assessed by calculation of the arthritic index (n=11–34 animals/group). The incidence of granuloma formation was assessed histologically as described in methods (n=11–23 animals/group). Statistical significance was determined by Fisher’s Exact Testing. * p < 0.05 vs. untreated. ** p <.007 vs. untreated.