Table 1.
Chemical and Biological Characterization of Turmeric Samples
| Curcuminoid Content (% by weight)
|
In vitro PGE2 Inhibition IC50 (μg extract/mL) | ||||
|---|---|---|---|---|---|
| Extract | total | curcumin (1) | demethoxy-curcumin (2) | bis-demethoxy-curcumin (3) | |
| Crude Turmeric Extract | 33.7 | 21.4 | 7.2 | 5.1 | 0.13 |
| Essential Oil-Depleted Turmeric Fraction | 40.6 | 25.7 | 8.7 | 6.2 | 0.48 |
| Purified Curcuminoids (commerical curcumina) | 93.6 | 74.2 | 14.9 | 4.5 | 2.66 |
a
Although labeled as “98+% curcumin”, this product contained all three curcuminoids with total curcuminoid content < 98%.