. Author manuscript; available in PMC: 2008 Sep 12.

Published in final edited form as: J Am Chem Soc. 2006 May 3;128(17):5913–5922. doi: 10.1021/ja060943h

Table 3.

Co-expression of Interacting Proteins

PDZ Domain	Interacting Partner	Tissues in which the genes for both proteins are expressed^a
PSD95	Scn5a	Preoptic
Chapsyn-110	Cnksr2	Amygdala^b, frontal cortex^b, preoptic, cerebellum^b, cerebral cortex^b, dorsal root ganglia, dorsal striatum^b, hippocampus^b, hypothalamus, olfactory bulb
Chapsyn-110	Mapk12	Cerebellum, dorsal root ganglia, main olfactory epithelium
Chapsyn-110	Scn5a	Preoptic, main olfactory epithelium
SAP102	Kv1.4	Olfactory bulb
SAP102	Cnksr2	Amygdala, frontal cortex, preoptic, cerebral cortex, dorsal striatum, hippocampus, olfactory bulb
SAP102	KIF1B	Amygdala, frontal cortex, preoptic, cerebral cortex, dorsal striatum, hippocampus, olfactory bulb
Scn5a	Scn5a	Preoptic
CIPP	Stargazin	Cerebellum^b, upper spinal cord, lower spinal cord
Shank3	Cnksr2	Amygdala, frontal cortex, preoptic, cerebellum^b, cerebral cortex^b, dorsal striatum^b, hippocampus^b, hypothalamus, olfactory bulb
PDZ-RGS3	Cnksr2	Cerebellum, dorsal root ganglia
PDZ-RGS3	Nrxn1/2	Trigeminal, cerebellum, dorsal root ganglia, main olfactory epithelium
Chapsyn-110	Scn4a	None
SAP102	Scn4a	None
SAP102	Mapk12	None
CIPP	Scn4a	None
Shank3	AN2	None

Genes were considered ‘expressed’ if their transcript levels were at least three-fold greater than the median transcript levels for that gene across all mouse tissues.

In these tissues, the genes for both proteins were expressed at levels that were more than ten-fold over the median.