Fig. 6.

Schematic (not to scale) representation of the expression patterns of AQP0 and AQP1 in developing, postnatal and adult mouse lenses. At E11.25, fiber cells begin to express AQP0 (green). At E12.5, more fiber cells develop and express AQP0. At E17.5, AQP1 expression begins in the anterior epithelial cells (red); even more fiber cells are added and AQP0 expression continues. E19.0 and P2 show the gradual spreading of AQP1 expression toward the equatorial epithelial cells. P6.5 shows the expression of AQP1 in all of the epithelial cells and AQP0, in the fiber cells. P30 shows microcirculation; AQP1 expression reaches its maximum at P30. Microcirculation in the adult lens is depicted in the last picture of the series. E, embryonic stage; P, postnatal day; AQP0 in green; AQP1 in red; AE, anterior epithelial cells; DF, differentiating fiber cells; EQ, equatorial epithelial cells; F, fiber cells; LC, lens cavity; M, microcirculation; MF, matured fiber cells; N, lens nucleus.