Table 1.
Behavioral defects unc-64 mutants
| Strain | Locomotion
|
Pharyngeal pumps/min | Defecation
|
||
|---|---|---|---|---|---|
| Speed (μm/sec) | Efficiencya | Cycle time (s) | EMCb | ||
| N2c | 161 ± 36 | 0.63 | 250 ± 30 | 42.0 ± 3.3 | 98% |
| e246 | 13 ± 8 | 0.18 | 209 ± 20 | 39.3 ± 3.3 | 87% |
| js21 | 51 ± 22 | 0.43 | 234 ± 10 | 48.8 ± 9.2 | 80% |
| js115d | 0 | NA | 0.2 ± 0.6 | None | NA |
| js116d | 0 | NA | 3 ± 2 | None | NA |
Data shown as mean ± SD. A minimum of 18 animals were analyzed. NA, Not applicable.
a
Efficiency is defined as displacement/total distance traveled. unc-64 mutants have a tendency to alternate between forward and backward motion.
b
Percentage of defecation cycles with an enteric muscle contraction (EMC).
c
Data from Nonet et al. (1998).
d
L1 larvae scored less than 4 h after hatching.