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. 1999 May;10(5):1595–1608. doi: 10.1091/mbc.10.5.1595

Figure 2.

Figure 2

Figure 2

WRS-85D encodes a protein homologous to mammalian tryptophanyl-tRNA synthetases. (A) Genomic map of WRS-85D showing insertion site of l(3)03559/l(3)04410, cDNA mapping, and intron–exon boundaries. (B) Alignment between WRS-85D and mammalian TrpRS. Residues that are identical are black; residues that are similar are gray. The HVGH and KMSAS signature motifs are indicated with black lines above the sequence. Sequences for two WRS-85D splice forms are available at GenBank (accession numbers BankIt250528 AF125156 and BankIt250542 AF125157). (C) Developmental Northern blot showing expression profile throughout development. 0–2, 2–4, 4–8, 8–12, and 12–24, hours of embryogenesis; 1st, 2nd, and 3rd, three larval stages; P, pupae; S, Drosophila Schneider cells. The same Northern blot is shown hybridized to rp49 probe as a control for loading.