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. 2008 May 21;116(9):1218–1225. doi: 10.1289/ehp.11172

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Results of EMSA for NF-κB and AP-1 in aortic extracts. (A,B) DNA binding of AP-1 (A) and NF-κB (B) in aortic extracts from ApoE^−/− mice exposed to clean air (control; lanes 1–4) or to chrysotile asbestos for 3 days (lanes 5–8), 9 days (lanes 9–12 ), or 30 days (lanes 13–16). Data are expressed relative to OCT-1 compound as a loading control. Values in top portions of A and B are mean ± SE; error bars represent the variance of the averages of values obtained for each animal. (C,D) DNA binding of AP-1 (C) and NF-κB (D) in aortic extracts from DKO mice exposed to clean air (lanes 1–4) or to asbestos for 3 days (lanes 5–7), 9 days (lanes 8–11), or 30 days (lanes 12–14). Lane 15 represents a positive control. Arrows denote bands for respective transcription factor binding.

**p < 0.01 compared with control (n = 4 per group).