Table 3.
Effects of PM2.5 exposure on biomarkers of oxidative stress by supplementation groups.
Soy oil
|
Fish oil
|
|||
---|---|---|---|---|
β (SE) | p-Value | β (SE) | p-Value | |
Cu/Zn SOD | ||||
Intercept | 0.75 (0.03) | < 0.001 | 0.60 (0.06) | < 0.001 |
Supplementationa | 0.17 (0.09) | 0.050 | 0.29 (0.14) | 0.042 |
Indoor PM2.5 | −0.06 (0.02) | < 0.001 | −0.17 (0.05) | 0.002 |
Indoor (PM2.5)2b | — | 0.04 (0.02) | 0.009 | |
LPOc | ||||
Intercept | 4.15 (0.23) | < 0.001 | 3.96 (0.21) | < 0.001 |
Supplementationa | 0.49 (1.13) | 0.669 | −3.72 (1.04) | 0.002 |
Indoor PM2.5 | −0.02 (0.14) | 0.904 | −0.35 (0.19) | 0.080 |
Indoor (PM2.5)2 | — | 0.16 (0.07) | 0.024 | |
GSHd | ||||
Intercept | 1.21 (0.10) | < 0.001 | 1.44 (0.08) | < 0.001 |
Supplementationa | 0.70 (0.22) | 0.003 | 1.00 (0.19) | < 0.001 |
Indoor PM2.5 | −0.03 (0.04) | 0.406 | −0.09 (0.04) | 0.017 |
Data are regression coefficients; we adjusted models for date. For PM2.5, the coefficients correspond to a change in 10 μg/m3. Regression models for Cu/Zn SOD include 20 subjects and 74 observations in the soy oil group and 24 subjects and 90 observations in the fish oil group; for LPO, 21 subjects and 51 observations in the soy oil group and 21 subjects and 55 observations in the fish oil group; for GSH, 20 subjects and 76 observations in the soy oil group and 23 subjects and 86 observations in the fish oil group.
Reference category: presupplementation.
Linear relationship; indoor (PM2.5)2 does not apply.
Square root transformed.
Log transformed.