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. 2008 Sep;180(1):147–164. doi: 10.1534/genetics.108.089938

TABLE 5.

Genes both differentially expressed between pure dwarf and normal parental lines (P < 0.10) and with significant brain eQTL (α = 0.05)

Transcript namea Biological processa P-value of differential expressionb D/N common environmentc LGa Location (cM)a LRa Additive effecta PVE (%)a
Combined
CB496981 [GO] [Q24320] DNA-directed RNA polymerases I, II, and III subunit RPABC2 RNA synthesis 0.015 0.76 28m 70.4 19.1 0.66 28.8
CA044952 [GO] [P42281] Acyl-CoA-binding protein homolog (ACBP) Neural development 0.017 1.53 2m 72.8 20.1 −0.54 40.2
CK991017 [GO] [P00417] cytochrome c oxidase subunit 3 Metabolism and energy production 0.063 0.87 10f 8.0 19.3 −0.79 37.9
CA047976 Wu:fc15g08 protein [D. rerio] Unknown 0.064 1.25 36f 107.6 28.6 −1.23 78.3
CB492276 [GO] [P05213] tubulin α-2 chain Neural development 0.072 0.90 36f 105.6 20.5 −0.77 74.0
Female only
CN442540 [GO] [P00399] cytochrome c oxidase subunit 1 Metabolism and energy production 0.0074 0.81 26m 19.7 19.7 −0.81 63.8
CA044952 [GO] [P42281] Acyl-CoA-binding protein homolog (ACBP) Neural development 0.017 1.53 2m 70.8 22.2 −0.71 65.8
CB498203 pleiotrophic factor-α-2 precursor Unknown 0.028 0.85 12m 28.2 22.5 −0.32 50.9
CB511393 unknownd Unknown 0.049 0.85 3f, 26m 18.0,169.0 22.8, 23.4 −0.95, −0.94 78.2, 77.4
CB496460 [NR] [AAO32675] hyperosmotic glycine-rich protein [S. salar] Unknown 0.059 0.80 26m 20.0 22.7 −1.12 69.9
CA047976 Wu:fc15g08 protein [D. rerio] Unknown 0.064 1.25 36f 107.6 22.2 −1.23 78.5
CB492276 [GO] [P05213] tubulin α-2 chain (α-tubulin 2) (α-tubulin isotype M-α-2) Neural development 0.072 0.90 36f 107.6 23.1 −0.80 77.7
CB497444 [GO] [P68134] Actin, α cardiac Neural development 0.078 1.30 12f 90.2 22.6 1.01 58.7
CB511927 [GO] [P68369] tubulin α-chain Neural development 0.094 0.96 36f 107.6 25.7 −0.71 80.8
CB492855 [GO] [P62242] 40S ribosomal protein S8 Protein synthesis 0.097 1.25 5f 93.9 19.4 0.65 58.8
Male only
CK990568 [GO] [P56565] protein S100-A1 Neural plasticity 0.030 1.29 11f 70.4 22.3 −0.51 59.5
CA047133 [GO] [P02089] hemoglobin subunit β-1 Blood 0.063 0.85 21f 29.5 20.9 1.01 70.2
CB494514 [GO] [Q9VNE9] 60S ribosomal protein L13A Protein synthesis 0.076 1.25 2m 8.0 21.2 −0.80 62.8
CK990921 unknown Unknown 0.083 1.23 17f 83.5 19.3 −0.87 61.7
a

See Table 3 legend.

b

Based on F-test implemented in R/MAANOVA and eight individuals of each pure parental line.

c

Ratio of dwarf to normal mean expression values.

d

Only transcript for which more than one eQTL was detected; parameter estimates for each of these eQTL are separated by a comma.