TABLE 1.
Spectrum of discovered mutations
| This study
|
|||||
|---|---|---|---|---|---|
| Z2 | Z3 | Z2 + Z3 | Winkler et al. (2005) | Bentley et al. (2000) | |
| G/C to A/T (%) | 335 (69.9) | 1063 (75.5) | 1398 (74.1) | 37 (84) | 16 (100) |
| A to T (%) | 84 (17.5) | 218 (15.5) | 302 (16.0) | 5 (11) | 0 (0) |
| A/T to G/C (%) | 22 (4.6) | 51 (3.6) | 73 (3.9) | 1 (2) | 0 (0) |
| G/C to T/A (%) | 18 (3.8) | 46 (3.3) | 64 (3.4) | 0 (0) | 0 (0) |
| G to C (%) | 12 (2.5) | 20 (1.4) | 32 (1.7) | 0 (0) | 0 (0) |
| A/T to C/G (%) | 8 (1.7) | 10 (0.7) | 18 (1.0) | 1 (2) | 0 (0) |
| All point mutations (%) | 479 (100) | 1408 (100) | 1887 (100) | 44 (100) | 16 (100) |
| Multiple mutations | 22 | 50 | 72 | 0 | 0 |
| Small indels (<10 bp) | 15 | 20 | 35 | 0 | 0 |
| Large indels (≥10 bp) | 5 | 9 | 14 | 0 | 0 |
| Total mutations | 521 | 1487 | 2008 | 44 | 16 |
| TILLed amplicons | 44 | 104 | 148 | 10 | 2 |
| TILLed genes | 39 | 93 | 132 | 3 | 1 |