Table 1.

Reactions of Various Aldehydes

entry	RCHO	method	temp/time (h)	yielda (%)	Eeb (%)	Product
1		A	−35/48	53	92
		B	−25/21	56	91
2		A	−30/48	57	77
		B	−15/7	74	86
3		A	−30/48	64	83
		B	−15/22	46	87
4		A	−15/8	52	93
		B	−15/14	66	92
5		A	−35/36	51	90
		B	−20/10	56	91
6		A	−35/36	47	83
		B	−20/10	37	85
7a		B	−15/17	59	>99 de
7b		B	−15/18	33	71 de
8		B	−15/15	33	44
9		B	−15/14	50	91
10		A	−35/36	49	98

^aAll yields are for isolated pure product.

^bThe ee’s were determined by chiral hplc.