Table III.
Instructions for calculating the volume of donor red cells necessary to obtain the desired residual concentration of haemoglobin S after an isovolumetric red cell exchange
| Cell | Text to be entered |
|---|---|
| A1 | Kinetics of continuous flow red cell exchange – isovolumetric |
| A3 | Patient’s blood volume (mL) |
| A4 | Patient’s initial venous haematocrit (%) |
| A5 | Correction factor for the body haematocrit |
| A6 | Haematocrit of the removed blood (%) |
| A7 | Haematocrit of the transfused blood (%) |
| A8 | Initial concentration of HbS (%) |
| A9 | Desired final concentration of HbS (%) |
| A11 | Patient’s red cell volume (mL) |
| A12 | Volume of red cell concentrate to be exchanged (ml) |
| Value to be entered | |
| B3 | Blood volume of the patient (mL), e.g. 4,500 |
| B4 | Initial haematocrit of the patient, e.g. 30 |
| B5 | Correction factor for body haematocrit: 0.91 |
| B6 | Haematocrit of the removed blood (%), e.g. 80 |
| B7 | Haematocrit of the transfused blood (%), e.g. 60 |
| B8 | Initial concentration of HbS (%), e.g. 70 |
| B9 | Desired final concentration of HbS (%), e.g. 30 |
| Formula to be entered | |
| B11 | =B3*B4/100*B5 |
| B12 | = − B3*B5*B4/B7*LN(B9/B8) |