Table IV.
Instructions for calculating the volume of donor red cells necessary to obtain the desired final haematocrit and residual concentration of haemoglobin S after a non-isovolumetric red cell exchange
| Cell | Text to be entered |
|---|---|
| A1 | Kinetics of continuous flow red cell exchange – non-isovolumetric |
| A3 | Patient’s blood volume (mL) |
| A4 | Patient’s initial venous haematocrit (%) |
| A5 | Correction factor for the body haematocrit |
| A6 | Haematocrit of the removed blood (%) |
| A7 | Haematocrit of the transfused blood (%) |
| A8 | Initial concentration of HbS (%) |
| A9 | Desired final concentration of HbS (%) |
| A10 | Desired final haematocrit (%) |
| A12 | Patient’s initial red cell volume (mL) |
| A13 | Ratio between the transfused and the removed volumes |
| A14 | Volume of donor red cell concentrate necessary (mL) |
| Value to be entered | |
| B3 | Blood volume of the patient (mL), e.g. 4,500 |
| B4 | Initial haematocrit of the patient, e.g. 30 |
| B5 | Correction factor for body haematocrit: 0.91 |
| B6 | Haematocrit of the removed blood (%), e.g. 80 |
| B7 | Haematocrit of the transfused blood (%), e.g. 60 |
| B8 | Initial concentration of HbS (%), e.g. 70 |
| B9 | Desired final concentration of HbS (%), e.g. 30 |
| B10 | Desired final haematocrit (%), e.g. 33 |
| Formula to be entered | |
| B12 | =B3*B4/100*B5 |
| B13 | =1/(1+(LN(B10/B4)/LN(B9/B8))) |
| B14 | =B3*B5*(B10/100−B4/100)/(B7/100*(1−1/B13)) |