Table 2.

Specific infectivity and virus secretion in Huh7-25 cells

Clone	Intracellular HCV RNA (copies/well)	AIntracellular infectivity (FFU/well)	ASpecific intracellular infectivity (FFU/copies)	AExtracellular HCV RNA (copies/well)	AExtracellular infectivity (FFU/well)	Specific exracellular infectivity (FFU/copies)	Infectious virus secretion (extra/intra)
JFH-1 WT	4.40 × 107 ± 1.58 × 107	2.27 × 102 ± 5.17 × 101	1.09 × 10-5 ± 2.58 × 10-6	1.83 × 107 ± 1.95 × 106	6.17 × 103 ± 9.61 × 102	3.37 × 10-4 ± 1.38 × 10-3	7.20 ± 2.83
JFH-1 G838R	2.19 × 107 ± 1.11 × 106	9.89 × 102 ± 5.02 × 101	9.05 × 10-5 ± 2.76 × 10-6	5.14 × 107 ± 3.48 × 106	2.69 × 104 ± 6.96 × 103	5.33 × 10-4 ± 1.83 × 10-4	6.87 ± 2.07

The data are from day 3 after HCV RNA transfection of the Huh7-25 cells

^AP < 0.05 comparing JFH-1 WT and G838R