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. 1999 Jun;10(6):1719–1732. doi: 10.1091/mbc.10.6.1719

Figure 9.

Figure 9

Model for Vti1p function in membrane traffic. Sed5p forms a SNARE complex with Vti1p, Sft1p, and Ykt6p in retrograde traffic to the cis-Golgi compartment. Vti1p binds to Pep12p in transport of CPY from the TGN to the PVC. Vti1p interacts with Vam3p in transport of ALP from the Golgi to the vacuole and in transport of API from the cytoplasm to the vacuole. Nyv1p is only required for homotypic vacuolar fusion and forms a SNARE complex with Vam3p and Vam7p. Vti1p has been coimmunoprecipitated with Tlg1p and Tlg2p, but the functional relevance is not yet known.