Table 3. Genes whose expression was significantly (p less than or equal to 0.05) altered by more than two-fold.
|
Probe name |
p-value |
Mean log2 difference |
Hit definition |
E-value |
GO biological process term |
| UF_Oc_n_41285 |
0.001 |
4.48 |
Serum amyloid A-3 protein |
0 |
Acute-phase response |
| UF_Oc_n_41565 |
0.007 |
3.11 |
Interleukin-1 beta (IL-1 beta) |
0 |
Antimicrobial humoral response, inflammatory response |
| UF_Oc_n_41308 |
0.020 |
2.81 |
Alpha-1-acid glycoprotein (Orosomucoid) |
0 |
Acute-phase response, inflammatory response |
| UF_Oc_c_40013 |
0.000 |
2.07 |
Cathepsin K (EC 3.4.22.-) |
0 |
Lysosome, proteolysis and peptidolysis |
| UF_Oc_r_30389 |
0.012 |
1.87 |
Similar to Ldb1a |
8.46E-37 |
|
| UF_Oc_n_41283 |
0.008 |
1.85 |
92 kDa type IV collagenase (Matrix metalloproteinase-9) |
0 |
Collagen catabolism, collagenase activity |
| UF_Oc_c_40416 |
0.002 |
1.83 |
Neutrophil granules matrix glycoprotein SGP28 |
1.40E-20 |
Defense response, innate immune response, cell-cell adhesion |
| UF_Oc_r_30382 |
0.003 |
1.74 |
Ceruloplasmin At 3.0 angstrom |
1.04E-38 |
oxidoreductase activity |
| UF_Oc_c_40419 |
0.042 |
1.37 |
Lumican |
5.93E-20 |
Collagen binding, collagen fibril organization |
| UF_Oc_c_40194 |
0.010 |
1.32 |
Lysozyme C (1,4-beta-N-acetylmuramidase C) |
0 |
Lysozyme activity, response to bacteria, cell wall catabolism |
| UF_Oc_n_31501 |
0.011 |
1.28 |
Fibronectin |
0 |
Acute phase response, inflammatory response, cell adhesion and migration, extracellular matrix structural constituent |
| UF_Oc_n_41531 |
0.016 |
1.20 |
Serum amyloid A-1 |
0 |
Acute phase response |
| UF_Oc_c_40715 |
0.038 |
1.17 |
major facilitator family transporter |
1.18908 |
|
| UF_Oc_r_30531 |
0.003 |
1.11 |
Cathepsin B |
3.13E-06 |
Negative regulation of inflammatory response, proteolysis and peptidolysis |
| UF_Oc_n_41428 |
0.020 |
1.05 |
Cathepsin E (EC 3.4.23.34) |
0 |
Positive regulation of cytokine secretion, proteolysis and peptidolysis |
| UF_Oc_c_40213 |
0.048 |
1.05 |
Lumican |
0 |
Collagen binding, collagen fibril organization |
| UF_Oc_n_41539 |
0.009 |
1.04 |
Cystatin B |
0 |
|
| UF_Oc_c_40622 |
0.010 |
-1.00 |
NADH dehydrogenase subunit 4 |
0.335226 |
|
| UF_Oc_n_41502 |
0.022 |
-1.05 |
Voltage-dependent anion channel 1 |
0 |
Mitochondrial outer membrane |
| UF_Oc_n_41237 |
0.006 |
-1.06 |
Mono (ADP-ribosyl) transferase |
0 |
|
| UF_Oc_c_40346 |
0.040 |
-1.25 |
Corneal endothelium specific protein |
6.09E-38 |
|
| UF_Oc_n_41352 |
0.020 |
-1.35 |
Cytochrome P450 2A10 (CYPIIA10) |
0 |
Electron transport, oxidoreductase activity on paired donors, oxygen binding |
| UF_Oc_r_30067 |
0.004 |
-1.52 |
Alpha-actinin-2-associated LIM protein |
0 |
|
| UF_Oc_c_40478 |
0.024 |
-1.66 |
Corneal endothelium specific protein 1 |
6.32E-09 |
|
| UF_Oc_r_30565 |
0.006 |
-1.70 |
Hypothetical protein |
0.00204271 |
|
| UF_Oc_n_41489 | 0.008 | -2.06 | Chondromodulin-I (Leukocytecell-derived chemotaxin 1) | 0 | Cell differentiation, extracellular space |
Mean log2 difference is the level of gene expression in tissue surrounding the surgical site compared to similar tissue from the nonsurgically treated control eye. The p-value represents the level of significance in treatment means, hit definition the name of the most homologous gene and E-value the level of confidence that the matched name is incorrect. Also listed are the GeneOntology Consortium terms for biological process associated with the most homologous gene.