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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Jun 28;18(15):4312–4315. doi: 10.1016/j.bmcl.2008.06.087

Figure 5.

Figure 5

The final model of PAMAM-CGS21680 with the fluorophore, 6 bound to the A2A AR homodimer. The carbon atoms of PAMAM and CGS21680 units are colored in green, carbon atoms of fluorophore are colored in cyan. The distances between the ribose ring oxygens (34.96 Å) and between Cα atoms of the N-terminal Met residue of each A2A subunit (66.86 Å) were measured. The overall height of the complex of the receptor dimer with the dendrimer bound is about 110 Å.