Figure 1.
Structures of polymerizable peptide derivatives and HPMA copolymer–peptide conjugates. PB, HPMA copolymer backbone labeled with a PEG3400-biotin graft; HPMA copolymer–peptide conjugates consist of three components: an HPMA copolymer backbone, a PEG-biotin graft used as a label for immunoassay, and peptide ligands with spacers of different lengths, A1, A2, A3, and A4. PB-A-B1, PB-A2-B1, PB-A3-B1, and PB-A4-B1, peptide B1 attached to the HPMA copolymer backbone via spacer A, A2, A3, and A4. PB-A2-P1, peptide P1 attached to the HPMA copolymer backbone via spacer A2.