Table 2.
Summary of domain specificity for all isolated antibodies (detailed in Tables 1a and 1b).
| Donor | Familiesa | Nb | PA20 | PA63 | D4 | NDc |
|---|---|---|---|---|---|---|
| 1 | 11 | 14 | 8 | 1 | 2 | 0 |
| 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | 16 | 20 | 12 | 1 | 0 | 3 |
| 4 | 13 | 24 | 8 | 5 | 0 | 0 |
| 5 | 14 | 28 | 7 | 4 | 3 | 0 |
| 6 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | 8 | 33 | 3 | 3 | 0 | 2 |
| Totals | 64 | 121 | 40 | 14 | 5 | 5 |
a
Number of paratope families (as defined by unique B cell rearrangements) isolated for each donor.
b
Number of sequence unique, somatically-derived members of each family isolated.
c
Domain specificity could not be assigned.