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Inhibition of NQO1 activity in MIA PaCa-2 cells treated with indolequinones. NQO1 activity was measured in MIA PaCa-2 cells following treatment with indolequinones (1 nM-10 μM) for 1 h. Results are the mean ± standard deviation of three separate determinations. Open circles, 24; open diamonds, 23; open squares, 22; open triangles, 12; closed circles, 6; closed squares, 19.
