Table 2.
Parameter | Genotypes | No. | Monocytes | Neutrophils | ||||
*Low | High | Total | Low | High | Total | |||
**C1291T | CC | 28 | 29.57 ± 1.54 | 57.00 ± 1.81 | 86.57a ± 0.96 | 73.25 ± 2.52 | 4.48 ± 0.62 | 77.74 ± 2.73 |
CT | 30 | 28.25 ± 1.48 | 61.26 ± 1.75 | 89.51b ± 0.93 | 76.21 ± 2.43 | 5.54 ± 0.60 | 81.75 ± 2.64 | |
TT | 6 | 32.02 ± 3.32 | 58.94 ± 3.91 | 90.97b ± 2.07 | 81.57 ± 5.43 | 4.11 ± 1.34 | 85.68 ± 5.91 | |
A1908G (Asn175Asp) | AA | 51 | 29.10 ± 1.14 | 59.12 ± 1.36 | 88.22 ± 0.74 | 75.25 ± 1.88 | 4.36A ± 0.43 | 79.60 ± 2.03 |
AG | 13 | 29.49 ± 2.26 | 59.39 ± 2.70 | 88.88 ± 1.47 | 76.09 ± 3.72 | 7.26B ± 0.86 | 83.35 ± 4.03 | |
Haplotypes | CAAAG, CAAAG | 28 | 29.57 ± 1.56 | 57.00 ± 1.82 | 86.57a ± 0.97 | 73.25 ± 2.55 | 4.48a ± 0.59 | 77.74 ± 2.78 |
CAAAG, TAGGT | 20 | 27.75 ± 1.84 | 62.46 ± 2.16 | 90.21b ± 1.14 | 77.36 ± 3.01 | 4.45a ± 0.70 | 81.81 ± 3.28 | |
CAAAG, TGGGT | 10 | 29.24 ± 2.60 | 58.85 ± 3.05 | 88.09a ± 1.61 | 73.90 ± 4.26 | 7.73bc ± 0.98 | 81.63 ± 4.65 | |
TAGGT, TGGGT | 3 | 30.33 ± 4.75 | 61.18 ± 5.56 | 91.51a ± 2.95 | 83.41 ± 7.78 | 5.68ab ± 1.80 | 89.08 ± 8.48 | |
TAGGT, TAGGT | 3 | 33.72 ± 4.75 | 56.72 ± 5.56 | 90.42a ± 2.95 | 79.73 ± 7.78 | 2.55a ± 1.80 | 82.28 ± 8.48 |
a, b, c or A, BMeans for each parameter and within the same column differ significantly. a, b, c indicates significance (P < 0.05) with non adjusted means while A, B indicate significance with both non-adjusted means and when Scheffe's adjustments were applied to means (P < 0.01). SNPs 1291, 2318 and 2601 are in 100% linkage disequilibrium and possess the same information, like wise are gene alleles and haplotypes. Only values for SNP1291 and haplotypes have been represented in the table.
*Low indicates the percentage of cells in the region of Log101 to 102, high > log102 and total, all cells stained.
**SNP numbering is according to GenBank No. EU148609 and amino acid residue numbering is according to GenBank No. ABV68569.