Table 2.

MatInspector promoter analysis of modules present in three of the four co-regulated tooth-specific genes. Modules denote the family of transcription factors with members that bind to the core binding site. TFBS nucleotides in capitol letters denote the core sequence. Lower case nucleotides in bold and underlined denote base pairs that are observed in the TFBS at an occurrence of greater than 60%. TFBS, transcription factor binding site; TSS, transcription start site.

	Ambn	Amelx	Enam	Mmp20
Module 1	HOMF/BRNF		HOMF/BRNF	HOMF/BRNF
TFBS	TAATt/gCACAttttt		TAATt/atagtTAAT	TAATt/acatgaACTAt
Strand Specificity	+/+		+/+	+/+
bp Separating TFBS	16		12	20
bp from TSS	64		375	83
Module 2	BRNF/TPBF		BRNF/TPBF	BRNF/TPBF
TFBS	gCACAttttt/ttTAAA		atagaTAAT/aTAAA	acatgaACTAt/aTAAAa
Strand Specificity	+/+		+/+	+/+
bp Separating TFBS	48		46	39
bp from TSS	18		124	45
Module 3		HOXF/BRNF	HOXF/BRNF	HOXF/HOXF/BRNF
TFBS		TAAA/tatATTT	TAAT/atagtTAAT	TAAA/cTAAT/tttATTT
Strand Specificity		+/-	+/-	+/+/-
bp Separating TFBS		17	11	42, 16
bp from TSS		236	375	262
Module 4		HOXF/HOXC	HOXF/HOXC	HOXF/HOXF/HOXC & HOXF/HOXC
TFBS		TTAATc/aTGATtttt	TAAT/TGATatat	TAAA/cTAAT/tTGATttat & TAAT/gtGATTgac
Strand Specificity		+/-	+/-	+/+/- & +/-
bp Separating TFBS		42	17	44, 37 & 18
bp from TSS		106	370	261 & 181