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Bottom: model-predicted glucagon rebound response to a switch-off signal (94:30–95:00) in the face of low-glucose conditions in streptozotocin (STZ)-treated rats. Top: GCR response in a representative animal from the Somatostatin switch-off group aligned in a way that the times of the switch-off in the 2 plots coincide (t = 95:00). Vertical dotted lines mark the time period studied in the experiment. BG, blood glucose.
