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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Cancer Res. 2008 Aug 1;68(15):6136–6144. doi: 10.1158/0008-5472.CAN-08-0464

Figure 2. MUC1-C is sufficient for inhibition of caspase-8 activation and apoptosis.

Figure 2

A. U-937 cells were infected with retroviruses expressing the control pLXIN vector or pLXIN-MUC1-C. Lysates were immunoblotted with the indicated antibodies. B. Lysates from the indicated U-937 cells treated with 10 ng/ml TNFα were immunoblotted with the indicated antibodies. C. The indicated U-937 cells were treated with 10 ng/ml TNFα or 50 ng/ml FasL for 24 h and monitored for sub-G1 content. D. The results are expressed as the percentage apoptosis (mean±SD of three experiments).