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Impact of Sex, Age, Tumor Stage, Tumor Grade, and Smoking History on RUNX3 Methylation (PMR ≥ 10%, N=304)
| OR (95% CI) | p-value | |
|---|---|---|
| Age at Diagnosis | 0.0311 | |
| 1-Year Increase | 1.04 (1.00, 1.08) | |
| Sex | 0.491 | |
| Female | 1.00 (reference) | |
| Male | 1.23 (0.68, 2.20) | |
| Tumor Stage & Grade | 0.0101 | |
| Ta - Low | 1.00 (reference) | |
| Ta – High/CIS/T1 | 1.18 (0.68, 2.07) | |
| T2+ | 2.16 (1.18, 3.94) | |
| Smoking | 0.0151 | |
| Never/Irregular | 1.00 (reference) | |
| Former/Current | 2.76 (1.15, 6.66) |
p-value based on likelihood ratio test.
