Table 1.

Quantification of tubular necrosis from Trichrome stained slides from treated animals. Slides were blinded and ten photographs of cortical areas per treatment group were taken, which covered an estimated 10% of the surface area in a random fashion. Areas of renal damage, which were determined by tubular necrosis, were identified and quantified by amount of necrosis per photograph. Each photograph was divided into ten blocks, and the number of blocks that contained necrotic tubules per photo was recorded. Data is represented as % damaged in each treatment group. # = significant difference for CyA treated.

	Blocks Damaged	Percent Damaged
Control	0	0
Vehicle	Trace	Trace
CyA	29/70	41%
CyA + Apocynin	22/60	36%
CyA + IL-6 Ab	6/40 #	15% #