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. 2008 Jul 2;295(3):R773–R780. doi: 10.1152/ajpregu.00727.2007

Fig. 5.

Fig. 5.

A: serum leptin at day 60 in 3- and 30-mo-old rats on chow or HF diets. Ages represent the age of the animal when HF or chow feeding was begun. Assessments were determined 60 days later. Values are means ± SE of 3- (n = 9–10) and 30-mo-old (n = 9–13) rats. P < 0.0001 for the difference with HF feeding and difference with age by two-way ANOVA; P = 0.0041 for the interaction. *P < 0.05 for the difference between chow-fed young and aged rats by post hoc analysis. **P < 0.001 for the difference between HF-fed young and aged rats by post hoc analysis. †P < 0.05 for the difference between chow-fed and HF-fed young rats by post hoc analysis. ††P < 0.001 for the difference between chow-fed and HF-fed aged rats by post hoc analysis. B: white adipose tissue at death from 3- and 30-mo-old rats following chow or HF feeding. Ages represent the age of the animal when HF or chow feeding was begun. Assessments were determined 60 days later. Values are means ± SE of 3- (n = 10–12) and 30-mo-old (n = 8–14) rats. P < 0.0001 for the difference with HF feeding and difference with age by two-way ANOVA. *P < 0.001 for the difference between chow-fed young and aged rats by post hoc analysis. **P < 0.001 for the difference between HF fed young and aged rats by post hoc analysis. †P < 0.001 for the difference between chow-fed and HF-fed young rats by post hoc analysis. ††P < 0.001 for the difference between chow-fed and HF-fed aged rats by post hoc analysis.