Fig. 6.

Voluntary wheel running over a 4-day period. Wheel running activity was determined 2 mo after HF or chow feeding for rats initially 3 or 30 mo of age and after 5 mo of HF or chow feeding in rats initially 6, 12, or 18 mo of age. Ages represent the age at the time of wheel running. Values are means ± SE. *P < 0.001 for the difference between 5- and 32-mo-old chow-fed rats. †P < 0.001 for the difference between 5-mo-old chow-fed and 5-mo-old HF fed rats. **P < 0.01 for the difference between 5-mo-old HF fed and all other HF-fed groups by post hoc analysis.