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A: change in body weight during a 7-day peripheral leptin infusion in 30-mo-old chow-fed rats. Values are means ± SE of 7–8 per group. P = 0.9975 for the difference with leptin treatment by one-way ANOVA. B: change in food intake in aged rats during a 7-day peripheral leptin infusion. Values are means ± SE of 30-mo-old chow-fed rats (n = 7–8 per group). There was no difference (P = 0.087) in cumulative food intake with leptin treatment.
