Table 2.
Sham Clipped |
2K,1C
|
|||
---|---|---|---|---|
Sham Lesioned | SFOx | Sham Lesioned | SFOx | |
n | 7 | 6 | 8 | 5 |
HR | ||||
Upper plateau, beats/min | 505±19 | 532±8 | 523±13 | 484±14e |
Lower plateau, beats/min | 267±17 | 308±25 | 331±14c | 348±19 |
Range, beats/min | 238±11 | 224±33 | 190±8c | 135±15b |
BP50, mmHg | 131±5 | 121±4 | 149±4c | 135±9 |
Slope coefficient | 0.06±0.01 | 0.06±0.01 | 0.05±0.01 | 0.07±0.01 |
Gmax, −beats·min−1·mmHg−1 | 3.39±0.48 | 2.91±0.40 | 2.50±0.33 | 2.27±0.40 |
RSNA | ||||
Upper plateau, % | 297±31 | 528±56b | 328±28 | 209±21a,e |
Lower plateau, % | 12±3 | 42±6b | 27±8 | 32±11 |
Range, % | 285±31 | 487±53b | 302±27 | 176±23b,e |
BP50, mmHg | 117±3 | 108±5 | 147±5d | 131±3a,e |
Slope coefficient | 0.11±0.02 | 0.10±0.01 | 0.08±0.01 | 0.08±0.01 |
Gmax, −%/mmHg | 8.25±1.52 | 12.68±2.40 | 6.18±0.48 | 3.52±0.74b,e |
Values are means ± SE; n = no. of animals. BP50, MAP at midpoint of curve; Gmax, maximum gain; RSNA, renal sympathetic nerve activity;
P < 0.05;
P < 0.01 vs. corresponding sham-lesioned group.
P < 0.05;
P < 0.005 vs. sham-clipped, sham-lesioned group.
P < 0.02 vs. sham-clipped SFOx group.