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. 2008 Jul 2;295(3):R741–R750. doi: 10.1152/ajpregu.00157.2008

Table 2.

HR and RSNA baroreflex curve parameters in sham-lesioned and SFOx sham-clipped and 2K,1C rats


Sham Clipped
2K,1C
Sham Lesioned SFOx Sham Lesioned SFOx
n 7 6 8 5
HR
    Upper plateau, beats/min 505±19 532±8 523±13 484±14e
    Lower plateau, beats/min 267±17 308±25 331±14c 348±19
    Range, beats/min 238±11 224±33 190±8c 135±15b
    BP50, mmHg 131±5 121±4 149±4c 135±9
    Slope coefficient 0.06±0.01 0.06±0.01 0.05±0.01 0.07±0.01
    Gmax, −beats·min−1·mmHg−1 3.39±0.48 2.91±0.40 2.50±0.33 2.27±0.40
RSNA
    Upper plateau, % 297±31 528±56b 328±28 209±21a,e
    Lower plateau, % 12±3 42±6b 27±8 32±11
    Range, % 285±31 487±53b 302±27 176±23b,e
    BP50, mmHg 117±3 108±5 147±5d 131±3a,e
    Slope coefficient 0.11±0.02 0.10±0.01 0.08±0.01 0.08±0.01
    Gmax, −%/mmHg 8.25±1.52 12.68±2.40 6.18±0.48 3.52±0.74b,e

Values are means ± SE; n = no. of animals. BP50, MAP at midpoint of curve; Gmax, maximum gain; RSNA, renal sympathetic nerve activity;

a

P < 0.05;

b

P < 0.01 vs. corresponding sham-lesioned group.

c

P < 0.05;

d

P < 0.005 vs. sham-clipped, sham-lesioned group.

e

P < 0.02 vs. sham-clipped SFOx group.