Fig. 2.
The effect of 1 wk and 4 mo of high fat (HF) feeding on ACE2 mRNA expression (left) and activity (right) in epididymal (EF; top) and subcutaneous (SubQ; bottom) adipose tissues. Top, left: ACE2 mRNA expression in EF increased at 1 wk and 4 mo of HF feeding compared with low fat (LF). Top, right: ACE2 activity in epididymal fat (EF) increased at 1 wk, but not at 4 mo of HF feeding compared with LF. Bottom, left: ACE2 mRNA in SubQ adipose tissue increased at 1 wk and 4 mo of HF feeding compared with LF. Bottom, right: ACE2 activity in SubQ adipose tissue was increased at 1 wk, but not at 4 mo of HF feeding compared with LF. Data are expressed as means ± SE from n = 10 mice/time point/diet. *Significantly different from LF, P < 0.05.