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Effect of glivec on whole rat bladder sheets. A: effect of 30 μM glivec on spontaneous activity in bladder sheets from a normal adult rat (top) and a spinal cord-transected (SCT) rat (bottom). The calibration bars are relevant to both traces. B: Ca2+ isochronal maps from an SCT rat bladder sheet (i), an SCT rat bladder sheet in the presence of glivec (30 μM; ii), and after washout of glivec (iii). Isochrones represent successive conduction delays of 44 ms.
