Fig. 3.
Effect of incrementing bath osmolality on superoxide production in mTAL obtained from SS and SS.13BN rats. A: comparison of O2− response in SS (○; n = 7) and SS.13BN (•; n = 7) mTAL of rats fed a 0.4% NaCl diet in response to incrementing bath osmolality using choline-chloride (ChCl) in the presence of 100 μM N-methyl-amiloride (SS and SS.13BN data appear superimposed). B: comparison of O2− response in SS (n = 6) and SS.13BN (n = 6) mTAL of rats fed a 0.4% NaCl diet in response to incrementing bath osmolality using ChCl in the presence of 4 mM ouabain. C: O2− response in SS (n = 6) mTAL of rats fed 0.4% NaCl in response to incrementing bath osmolality using urea. *Area identified under time point = P < 0.05 for differences between strains, as determined by Bonferroni post hoc test.