Fig. 5.

Effect of oxidative stress on ANG II-induced Na/H exchanger 3 stimulation in renal proximal tubules from C, BSO-, T-, and BSO+T-treated rats. A: renal proximal tubules were challenged with 10 pM ANG II for 10 min. B: renal proximal tubules were incubated with 1 μM Can or PD followed by challenge with 10 pM ANG II for 10 min. Bars represent means ± SE of 6–8 different experiments performed in triplicate. *P < 0.05 vs. basal. ∞P < 0.05 vs. BSO. #P < 0.05 vs. C + Can. $P < 0.05 vs. BSO + Can. ΦP < 0.05 vs. C. ΨP < 0.05 vs. C + PD using 1-way ANOVA followed by post hoc Newman-Keuls multiple test.