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Monoamine levels in brain areas of wild-type (wt) and Go2α−/− mice. Serotonin, noradrenaline, and dopamine were analyzed in extracts from frozen brains or brain areas using HPLC. A) Until day P8, there are no significant differences in whole brain monoamine concentrations between wt and Go2α−/− mice. B) In the striatum of P12 and adult Go2α−/− animals, dopamine amounts are decreased compared to wt littermates. Values represent means ± se; n = 6. *P < 0.05.
