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. 2008 Oct;22(10):3571–3580. doi: 10.1096/fj.08-111401

Figure 5.

Figure 5.

Effect of VEGF-164 on mouse luminal epithelial (LE) cell migration in an in vitro scratch wound assay. LE cells were either cocultured with stromal or bEnd3 (endothelial) cells in transwell inserts. LE cell migration was determined in scratch wounds in serum-free medium (SFM) alone or SFM plus VEGF-164 (VEGF) with or without VEGF Trap or neutralizing antibodies against VEGFR1 (αVEGFR1), VEGFR2 (αVEGFR2), NP1 (αNP1), or αVEGFR2+ αNP1. A, B) Analysis of LE cell migration in scratch wounds cocultured with stromal (A) or endothelial (B) cells in the presence of VEGF or VEGF plus different VEGF inhibitors. The first bars in A (SFM no SC) and B (SFM no EC) show LE cell migration without coculture. Bar graphs represent means ± se; *P < 0.05.