Table 1.

Top-10 SCAN clusters with highest p-values

	Cluster ID	P -value	GO Term	Term Freq. in Network	Term Freq. in Cluster	Cluster Size
Biological Process	1	4.45E-98	nuclear mrna splicing, via spliceosome	66	58	88
	89	1.01E-65	translation	252	58	64
	5	1.16E-52	ubiquitin-dependent protein catabolic process	60	34	56
	2	9.04E-40	transcription from rna polymerase ii promoter	50	41	288
	15	8.58E-38	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	13	13	13
	22	1.36E-30	chromatin remodeling	46	20	40
	192	5.46E-29	vacuolar acidification	23	13	16
	13	6.36E-29	chromosome segregation	36	16	25
	24	2.14E-28	regulation of microtubule polymerization or depolymerization	10	10	12
	30	9.29E-28	regulation of cell growth	10	10	13
Cellular Components	7	6.81E-53	cytosolic large ribosomal subunit	80	55	222
	89	1.50E-51	mitochondrial small ribosomal subunit	33	29	64
	1	2.53E-41	u4/u6 × u5 tri-snrnp complex	27	25	88
	15	9.01E-36	anaphase-promoting complex	15	13	13
	22	7.15E-31	rsc complex	16	15	40
	24	2.14E-28	dash complex	10	10	12
	38	2.14E-28	trapp complex	10	10	12
	185	7.18E-26	ribonuclease mrp complex	9	9	11
	155	5.84E-25	smc5-smc6 complex	8	8	8
	53	4.93E-24	dna replication preinitiation complex	21	12	22
Molecular Functions	89	5.64E-71	structural constituent of ribosome	210	58	64
	5	2.75E-45	endopeptidase activity	26	24	56
	1	7.12E-45	contributes_to rna splicing factor activity, transesterification mechanism	29	27	88
	37	6.44E-41	snap receptor activity	24	23	74
	192	4.65E-28	hydrogen ion transporting atpase activity, rotational mechanism	12	11	16
	185	7.18E-26	contributes_to ribonuclease mrp activity	9	9	11
	22	6.60E-23	contributes_to dna-dependent atpase activity	15	12	40
	34	1.30E-22	protein transporter activity	24	14	46
	15	2.25E-18	ubiquitin-protein ligase activity	44	10	13
	8	1.37E-17	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	8	8	35