TABLE 2.
Activity of ciprofloxacin against 641 anaerobesa
| Bacterium (no. of isolates) | % of strains inhibited by ciprofloxacin at concn (μg/ml) of:
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | 128 | >128 | |
| Bacteroides fragilis (155) | 4 | 24 | 54 | 29 | 12 | 17 | 13 | 2 | ||||
| Bacteroides thetaiotaomicron (28) | 2 | 8 | 10 | 2 | 3 | 2 | 1 | |||||
| Other Bacteroides spp. (67) | 1 | 2 | 9 | 12 | 16 | 6 | 6 | 6 | 9 | |||
| B. fragilis group (250) | 1 | 4 | 26 | 65 | 49 | 38 | 25 | 22 | 10 | 10 | ||
| Prevotella spp. (55) | 6 | 9 | 12 | 6 | 7 | 5 | 5 | 3 | 1 | 1 | ||
| Fusobacterium spp. (40) | 4 | 3 | 1 | 8 | 13 | 11 | ||||||
| Porphyromonas spp. (20) | 5 | 2 | 8 | 4 | 1 | |||||||
| Bilophila wadsworthia (19) | 2 | 10 | 5 | 1 | 1 | |||||||
| Other gram-negative bacilli (2) | 1 | 1 | ||||||||||
| Veillonella spp. (19) | 16 | 1 | 1 | 1 | ||||||||
| All gram-negative anaerobes (405) | 33 | 14 | 19 | 34 | 50 | 84 | 56 | 43 | 28 | 23 | 11 | 10 |
| Clostridium spp. (54) | 1 | 11 | 13 | 11 | 6 | 1 | 2 | 5 | 3 | 1 | ||
| Clostridium difficile (46) | 2 | 9 | 24 | 1 | 1 | 9 | ||||||
| Bifidobacterium spp. (12) | 1 | 3 | 6 | 2 | ||||||||
| Eggerthella lenta (12) | 5 | 3 | 2 | 2 | ||||||||
| Eubacterium aerofaciens (4) | 1 | 2 | 1 | |||||||||
| Actinomyces spp. (1) | 1 | |||||||||||
| Propionibacterium spp. (21) | 9 | 11 | 1 | |||||||||
| Gram-positive cocci (86) | 5 | 6 | 17 | 27 | 13 | 11 | 1 | 1 | 4 | 1 | ||
| All gram-positive anaerobes (236) | 12 | 20 | 42 | 52 | 25 | 19 | 5 | 12 | 33 | 5 | 1 | 10 |
a
For details, see the footnotes to Table 1.