TABLE 4.
Activity of moxifloxacin against 641 anaerobesa
| Bacterium (no. of isolates) | % of strains inhibited by moxifloxacin at concn (μg/ml) of:
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤0.06 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | >64 | |
| Bacteroides fragilis (155) | 19 | 40 | 40 | 23 | 14 | 8 | 4 | 6 | 1 | |||
| Bacteroides thetaiotaomicron (28) | 1 | 4 | 13 | 5 | 2 | 1 | 1 | 1 | ||||
| Other Bacteroides spp. (67) | 5 | 8 | 18 | 12 | 8 | 7 | 5 | 2 | 2 | |||
| B. fragilis group (250) | 19 | 46 | 52 | 54 | 31 | 18 | 12 | 12 | 1 | 2 | 3 | |
| Prevotella spp. (55) | 12 | 2 | 3 | 10 | 12 | 9 | 4 | 1 | 2 | |||
| Fusobacterium spp. (40) | 7 | 6 | 11 | 12 | 1 | 3 | ||||||
| Porphyromonas spp. (20) | 6 | 1 | 6 | 7 | ||||||||
| Bilophila wadsworthia (19) | 3 | 13 | 2 | 1 | ||||||||
| Other gram-negative bacilli (2) | 1 | 1 | ||||||||||
| Veillonella spp. (19) | 4 | 11 | 3 | 1 | ||||||||
| All gram-negative anaerobes (405) | 25 | 32 | 81 | 98 | 69 | 43 | 22 | 15 | 12 | 3 | 2 | 3 |
| Clostridium spp. (54) | 1 | 5 | 13 | 17 | 7 | 2 | 5 | 4 | ||||
| Clostridium difficile (46) | 2 | 23 | 10 | 1 | 2 | 7 | 1 | |||||
| Bifidobacterium spp. (12) | 4 | 5 | 3 | |||||||||
| Eggerthella lenta (12) | 3 | 6 | 2 | 1 | ||||||||
| Eubacterium aerofaciens (4) | 3 | 1 | ||||||||||
| Actinomyces spp. (1) | 1 | |||||||||||
| Propionibacterium spp. (21) | 1 | 11 | 8 | 1 | ||||||||
| Gram-positive cocci (86) | 7 | 20 | 24 | 26 | 3 | 2 | 1 | 2 | 1 | |||
| All gram-positive anaerobes (236) | 12 | 26 | 54 | 60 | 19 | 31 | 16 | 7 | 3 | 7 | 1 | |
a
For details, see the footnotes to Table 1.