TABLE 9.
Activity of clindamycin against 641 anaerobesa
| Bacterium (no. of isolates) | % of strains inhibited by clindamycin at concn (μg/ml) of:
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤0.06 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | >64 | |
| Bacteroides fragilis (155) | 6 | 6 | 21 | 50 | 31 | 18 | 6 | 1 | 16 | |||
| Bacteroides thetaiotaomicron (28) | 2 | 1 | 1 | 6 | 6 | 2 | 2 | 8 | ||||
| Other Bacteroides spp. (67) | 6 | 1 | 5 | 9 | 12 | 8 | 1 | 1 | 24 | |||
| B. fragilis group (250) | 14 | 6 | 22 | 56 | 41 | 36 | 20 | 4 | 3 | 48 | ||
| Prevotella spp. (55) | 40 | 2 | 4 | 5 | 1 | 1 | 2 | |||||
| Fusobacterium spp. (40) | 21 | 14 | 2 | 1 | 1 | 1 | ||||||
| Porphyromonas spp. (20) | 20 | |||||||||||
| Bilophila wadsworthia (19) | 2 | 6 | 11 | |||||||||
| Other gram-negative bacilli (2) | 2 | |||||||||||
| Veillonella spp. (19) | 4 | 5 | 10 | |||||||||
| All gram-negative anaerobes (405) | 103 | 33 | 49 | 62 | 42 | 38 | 20 | 4 | 3 | 1 | 50 | |
| Clostridium spp. (54) | 17 | 2 | 2 | 4 | 2 | 4 | 10 | 2 | 3 | 1 | 7 | |
| Clostridium difficile (46) | 2 | 6 | 18 | 2 | 18 | |||||||
| Bifidobacterium spp. (12) | 9 | 2 | 1 | |||||||||
| Eggerthella lenta (12) | 7 | 1 | 2 | 2 | ||||||||
| Eubacterium aerofaciens (4) | 3 | 1 | ||||||||||
| Actinomyces spp. (1) | 1 | |||||||||||
| Propionibacterium spp. (21) | 1 | 10 | 2 | 3 | 3 | 1 | 1 | |||||
| Gram-positive cocci (86) | 31 | 14 | 10 | 10 | 8 | 3 | 3 | 2 | 1 | 2 | 1 | 1 |
| All gram-positive anaerobes (236) | 69 | 28 | 16 | 18 | 13 | 10 | 15 | 10 | 22 | 6 | 2 | 27 |
a
For details, see the footnotes to Table 1.