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Correlations between decrease in bacterial counts of P. aeruginosa per milliliter after 8 h of exposure to levofloxacin at concentrations determined from individual concentration-time profiles of levofloxacin in muscle tissue and individual Cmax muscle/MIC ratios (a), AUC0-8 muscle/MIC ratios (b), and AUC0-8 muscle/AUC0-8 plasma free ratios (c). A P value <0.05 was considered significant.
