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Amino acid sequences of the TM domains (bold) and CTs of Japan/305/57 HA WT and HA chimeras constructed for functional studies. The HA constructs are designated H-X-Y, where H is the ectodomain of HA, X is the origin of the TM domain (shown in bold letters), and Y the source of the CT. H denotes HA, P pIgR, and E the env protein of Rous sarcoma virus. A CT of P* symbolizes that the normal CT of pIgR was truncated to 11 amino acid residues to match the length of the CT of HA.
