TABLE 1.
No. of strains | Yrs of isolation | Antibiotic resistancea | Integron (cassettes/locationb)
|
Profilec
|
||
---|---|---|---|---|---|---|
Class 1 | Class 2 | PFGE | IS200 | |||
Multiresistant strains of the predominating clone | ||||||
81 | 1995-2001 | TMP, SPE, STR, SMX, NAL, AMP, KAN-NEO | dfrA1-sat1-aadA1/C | X8 | ISP9 | |
4 | 1995-2001 | TMP, SPE, STR, SMX, TET, NAL, AMP, GEN | dfrA1-aadA1/P or aadA1/P | dfrA1-sat1-aadA1/C | X8 | ISP9 |
Comparative strains | ||||||
5 | 1994-1999 | TMP, SPE, STR, SMX, TET, NAL, CHL, KAN-NEO | dfrA12-aadA2/P | X7 | ISP8 | |
9 | 1960-1993 | Sensitive | X1-X6 | ISP1-ISP7 |
Boldface indicates resistance exhibited by all strains, and lightface indicates resistance exhibited by only some strains. Abbreviations: TMP, trimethoprim; SPE, spectinomycin; STR, streptomycin; SMX, sulfamethoxazole; NAL, nalidixic acid; AMP, ampicillin; KAN-NEO, kanamycin-neomycin; TET, tetracycline; GEN, gentamicin; CHL, chloramphenicol.
P, high-molecular-weight plasmid; C, chromosome.
Assignment according to reference 18. X, XbaI; ISP, IS200 profile.