TABLE 3.

Estimated quinine MICs for different values of the parameters parasite multiplication rate, E_max, and slope γ

PMRa and γ values	Estimated MIC (μg/ml) (95% CI) for 1 − Emax values of:
	0.0001	0.00001	0.000001
PMR = 6
γ = 2.5	0.88 (0.84-0.92)	0.89 (0.84-0.93)	0.89 (0.85-0.93)
γ = 3.0	1.04 (1.00-1.08)	1.05 (1.01-1.08)	1.05 (1.01-1.08)
γ = 3.5	1.16 (1.12-1.20)	1.17 (1.13-1.21)	1.18 (1.14-1.22)
PMR = 10
γ = 2.5	0.54 (0.51-0.57)	0.55 (0.53-0.59)	0.56 (0.53-0.59)
γ = 3.0	0.68 (0.65-0.71)	0.71 (0.68-0.74)	0.71 (0.68-0.74)
γ = 3.5	0.80 (0.76-0.83)	0.84 (0.81-0.86)	0.84 (0.81-0.87)
PMR = 20
γ = 2.5	0.22 (0.19-0.24)	0.29 (0.27-0.31)	0.30 (0.28-0.31)
γ = 3.0	0.30 (0.27-0.33)	0.40 (0.38-0.42)	0.42 (0.40-0.44)
γ = 3.5	0.38 (0.35-0.41)	0.51 (0.48-0.53)	0.53 (0.51-0.55)

^aPMR, parasite multiplication rate.