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Transport of reducing equivalents among peroxisomes, cytoplasm, and mitochondria requires membrane-localized metabolite transporters. Indicated are proposed shuttles for malate/oxaloacetate, isocitrate/2-oxoglutarate, and glycerol-3-phosphate/dihydroxyacetonephosphate. The question mark indicates a cytosolic glycerol-3-phosphate dehydrogenase, of which the activity was measured in the cytosol (van Roermund, Hettema, and Tabak, unpublished observations).
