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. Author manuscript; available in PMC: 2008 Sep 16.
Published in final edited form as: J Med Chem. 2006 Oct 5;49(20):5932–5938. doi: 10.1021/jm0607294

Figure 2.

Figure 2

Influence of PALA (○) and PALI (●) on the active site of ATCase. Colorimetric assays were carried out at 25 °C in 50 mM Tris acetate buffer (pH 8.3) at saturating concentrations of carbamoyl phosphate (4.8 mM) and subsaturating concentrations of aspartic acid (2.4 mM). Relative activity represents the ratio of activity in the absence or presence of inhibitor to that in the absence of inhibitor.