Table 1.
Summary of behavioral, ERP, and LORETA findings for control (n=20) and depressed (n=20) subjects.
Control Subjects | MDD Subjects | p-value | |
---|---|---|---|
A. Behavioral performance | |||
Accuracy incongruent | 0.88±0.05 | 0.85±0.09 | n.s. |
Accuracy congruent | 0.93±0.05 | 0.93±0.06 | n.s. |
Stroop effect accuracy | −0.05±0.029 | −0.08±0.079 | n.s. |
RT incongruent | 511.61±69.50 | 561.27±124.15 | <0.001 |
RT congruent | 464.14±47.23 | 470.60±65.54 | n.s. |
Stroop effect RT | 47.47±35.69 | 90.67±70.29 | <0.02 |
B. Scalp ERP data | |||
N2 incongruent | 0.29±0.89 | 1.31±1.76 | <0.001 |
N2 congruent | 0.46±0.93 | 1.28±1.67 | <0.001 |
N450 incongruent | 2.38±1.67 | 2.91±2.20 | <0.001 |
N450 congruent | 2.91±1.60 | 3.13±2.14 | <0.05 |
C. LORETA data (620 ms) | |||
dACC incongruent | −3.70±0.17 | −3.76±0.15 | <0.07 |
dACC congruent | −3.75±0.19 | −3.70±0.10 | n.s. |
Δ(dACC)* | 0.05±0.11 | −0.06±0.11 | <0.005 |
Left DLPFC incongruent | −3.31±0.17 | −3.49±0.28 | <0.001 |
Left DLPFC congruent | −3.36±0.18 | −3.39±0.21 | n.s. |
Δ(left DLPFC)* | 0.50±0.13 | −0.10±0.18 | <0.005 |
The difference score (incongruent - congruent) was calculated at the time of maximal GFP (620 ms) within the N450 time window peak; n.s. = non-significant